Difficulties scaling proteomic studies have stifled its potential. But Encodia’s ProteoCode™ changes everything.
Our groundbreaking technology reverse translates peptide sequence information into a DNA library. This means scientists can improve scale of their research - to accelerate novel approaches to our most challenging diseases.
Our technology reverse translates peptide sequence information into a DNA library. This allows proteomics research to scale.
Affinity reagent binders with DNA barcode tags are introduced to the peptide-DNA chimera molecules. The identity of the affinity reagent is recorded when the DNA barcode tag binds to the peptide-DNA chimera.
After the affinity reagent tags bind to the DNA-peptide chimera, the ending amino acid is removed. This process is repeated for n-cycles to effectively sequence n-amino acids.
The result is a collection of billions of library elements, where each DNA barcode identifies an amino acid in the peptide.
